The life of white-collar New Yorker Peter (Nicolas Cage) seems to revolve solely around making as much money and sleeping with as many women as possible. After a typical night of scouring trendy bars for some action, Peter manages to take home the sexy Rachel (Jennifer Beals), who bites him on the neck while they're in bed. The next day, Peter is certain he is now a vampire. Though no one shares his point of view and he hasn't changed physically, he dons fake fangs and begins stalking women.

No sooner does Italian-American widow Loretta (Cher) accept a marriage proposal from her doltish boyfriend, Johnny (Danny Aiello), than she finds herself falling for his younger brother, Ronny (Nicolas Cage). She tries to resist, but Ronny lost his hand in an accident he blames on his brother, and has no scruples about aggressively pursuing her while Johnny is out of the country. As Loretta falls deeper in love, she comes to learn that she's not the only one in her family with a secret romance.

A disparate group of individuals takes refuge in an abandoned house when corpses begin to leave the graveyard in search of fresh human bodies to devour. The pragmatic Ben (Duane Jones) does his best to control the situation, but when the reanimated bodies surround the house, the other survivors begin to panic. As any semblance of order within the group begins to dissipate, the zombies start to find ways inside -- and one by one, the living humans become the prey of the deceased ones.

When unemployed ex-marine Michael Williams (Nicolas Cage) stumbles into a bar in Red Rock, Wyo., the owner, Wayne (J.T. Walsh), mistakes him for a hired killer and offers him $10,000 to kill his wife, Suzanne (Lara Flynn Boyle). Michael plays along, taking half the money up front, then tells Suzanne what her husband is planning. She seduces Michael and proposes that he kill her husband instead. While he weighs his options, the real killer (Dennis Hopper) turns up looking for his money.